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Under what circumstances can the new crown vaccine be mixed? China's disease control experts explain their doubts

  Chinanews.com, May 20. Under what circumstances can the new crown vaccine be mixed, and under what circumstances?  In response to this, at...

 Chinanews.com, May 20. Under what circumstances can the new crown vaccine be mixed, and under what circumstances? In response to this, at a press conference held on the 20th of the Joint Prevention and Control Mechanism of the State Council, relevant experts from CDC responded.

Data map: Citizens are vaccinated at a new crown vaccination point in a hospital. Photo by Qu Honglun

A question at a press conference said that recently, some members of the public reported that when two doses of the new crown vaccine were administered, they found that they belonged to different manufacturers. Will such "mixing" affect the efficiency of vaccination? Under what circumstances can mixed play, and under what circumstances?

"In this case, vaccines that occur on the same technical route as ours are generally used." Shao Yiming, a researcher at the China Centers for Disease Control and a member of the Vaccine R&D Team of the Scientific Research Group, responded that the main reason may be the vaccine. The supply was not in place for a while.

"We have done a large number of scientific research experiments before. In this case, the effect of using the same technical route of another manufacturer's vaccine is exactly the same, and it will neither affect the protection effect nor the safety of the vaccine. "Shao Yiming said.

Shao Yiming pointed out that our country, including the international community, has also seen some research data have appeared, and vaccines of different technical routes are also being "mixed", which is the real "mixed". The purpose of this "mixed" is to induce Stronger and longer lasting immune response. However, this has not yet been reviewed and determined by the drug regulatory department as a new immunization strategy, and it is still in the stage of data accumulation.

Shao Yiming said, "We have been paying attention, including our country is also carrying out research in this area."

In response to the above issues, Wang Huaqing, chief expert of the China Centers for Disease Control and Prevention’s immunization program, added that now we have approved three inactivated vaccines for the conditional marketing, including an adenovirus vaccine, and an emergency vaccine, a protein subunit vaccine. , Two kinds of inactivated vaccines. This includes three technical routes, one is the technical route of inactivated vaccines, and the other includes the technical route of protein subunits and the new technical route of adenovirus.

"Because the vaccine characteristics of different technical routes are different, this is why we have three injections, some two injections, and some one injection. This has a lot to do with the different technical routes, but the purpose is It is one, which is to ensure its effect and its safety." Wang Huaqing said.

Wang Huaqing said that in accordance with the technical guidelines for new crown virus vaccination, in principle, we recommend using products of the same technical route from the same company to complete its two-dose or three-dose vaccination.

"If there is no more supply of this vaccine in this area, or there is no supply of this vaccine for the time being, or there is another situation, it is a remote vaccination. For example, I completed the first dose in a certain place, but I went to work and go to another place. I live, and the local area does not provide this kind of vaccine, what should we do? We now require that if there is no special situation where the same company and the same technical route can be supplied, we recommend that the same technical route be used instead. Said that inactivated vaccines can only replace inactivated vaccines, and protein subunit vaccines can only replace protein subunit vaccines. Of course, adenovirus vaccines are only vaccinated once, and there is no such situation." Wang Huaqing said.

Wang Huaqing also pointed out that in the absence of sufficient argumentation and research evidence, it cannot be said that you have used an inactivated vaccine in the first place and replaced it with an adenovirus vaccine or a protein subunit vaccine. They cannot be "mixed". Vaccines of the same technical route can be vaccinated under special circumstances, but we still hope to be able to use the same company’s products to complete the entire vaccination process.

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